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Omeprazole CAS: 73590-58-6 |
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Omeprazole |
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73590-58-6 |
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CAS: 73590-58-6
Assay: 98.5% min. CP
Packing: 20Kg/cardboard drum
MF: C17H19N3O3S
MW: 345.42
Character: White Crystalline Solid. mp 156¡ÆC. solubility H2O: 0.5 mg/mL
Usage: Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative pharmaceutical raw materials.
Biological Activity: H + ,K + -ATPase inhibitor (IC 50 = 5.8 ¥ì M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 ¥ì M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 ¥ì M respectively) and blocks swelling-dependent chloride channels (ICIswell).
Contact: gck11@yccreate.com please leave your e-mail in the inquiry news! To your named place with 3 to 5 days by EMS or DHL Payment Terms: T/T, Western Union
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CAS: 73590-58-6
Assay: 98.5% min. CP
Packing: 20Kg/cardboard drum
MF: C17H19N3O3S
MW: 345.42
Character: White Crystalline Solid. mp 156¡ÆC. solubility H2O: 0.5 mg/mL
Usage: Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative pharmaceutical raw materials.
Biological Activity: H + ,K + -ATPase inhibitor (IC 50 = 5.8 ¥ì M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 ¥ì M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 ¥ì M respectively) and blocks swelling-dependent chloride channels (ICIswell).
Contact: gck11@yccreate.com please leave your e-mail in the inquiry news! To your named place with 3 to 5 days by EMS or DHL Payment Terms: T/T, Western Union
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