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Colchicine ¡¡ |
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Colchicine ¡¡ |
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Colchicine ¡¡ EINECS:200-598-5¡¡ Molecular Formula:C22H25NO6¡¡ CAS Registry Number:64-86-8¡¡ Molecular Weight:399.44¡¡ Density:1.32 g/cm3¡¡ Water solubility:45 g/L (20¡É)¡¡ Boiling Point:RELATIVE DENSITY¡¡ Melting Point:150-160¡ÉFlash Point:392.9¡ÆC¡¡ Alpha:-250 o (C=1,ALCOHOL)¡¡ Storage Temperature:Poison room¡¡ Refractive index:1.584¡¡ Solubility:¡¡ Biological Activity:Plant-derived alkaloid that binds to tubulin and depolymerizes microtubules.¡¡ Appearance:yellow powder¡¡ Stability:Stable. Light sensitive. Incompatible with strong oxidizing agents.¡¡ Usage:¡¡ An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal¡¡
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Colchicine ¡¡ EINECS:200-598-5¡¡ Molecular Formula:C22H25NO6¡¡ CAS Registry Number:64-86-8¡¡ Molecular Weight:399.44¡¡ Density:1.32 g/cm3¡¡ Water solubility:45 g/L (20¡É)¡¡ Boiling Point:RELATIVE DENSITY¡¡ Melting Point:150-160¡ÉFlash Point:392.9¡ÆC¡¡ Alpha:-250 o (C=1,ALCOHOL)¡¡ Storage Temperature:Poison room¡¡ Refractive index:1.584¡¡ Solubility:¡¡ Biological Activity:Plant-derived alkaloid that binds to tubulin and depolymerizes microtubules.¡¡ Appearance:yellow powder¡¡ Stability:Stable. Light sensitive. Incompatible with strong oxidizing agents.¡¡ Usage:¡¡ An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal¡¡
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