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estradiol benzoate
White powder
50-50-0
Estradiol benzoate (INN
brand names Agofollin, Diffolisterol, Progynon-B, many others), or oestradiol benzoate (BAN), is a synthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. It was the first form of estrogen to be marketed, patented by Schering-Kahlbaun in 1936 in an oil preparation for injectable use and introduced later that year as Progynon-B. Though it is still in widespread use today, it has been mostly superseded by newer forms of estradiol with improved pharmacokinetics that require less frequent administration such as estradiol cypionate and estradiol valerate.

Product Name: estradiol benzoate
Synonyms: beta-Estradiol-3-benzoate
Oestradiol Benzoate
17beta-Estradiol benzoate
1,3,5(10)-Estratriene-3,17b-diol 3-benzoate
3,17b-Dihydroxy-1,3,5(10)-estratriene 3-benzoate
(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate
CAS: 50-50-0
EINECS: 200-043-7
MF: C25H28O3
MW: 376.488
Assay: 99%
Appearance: White powder

Density 1.185g/cm3
Melting point 191-198¡É
Boiling point 531.2¡ÆC at 760 mmHg
Refractive index 1.604
Flash point 212¡ÆC
Vapour Pressur 4.08E-12mmHg at 25¡ÆC



2. Descriptions:

Estradiol benzoate (INN
brand names Agofollin, Diffolisterol, Progynon-B, many others), or oestradiol benzoate (BAN), is a synthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. It was the first form of estrogen to be marketed, patented by Schering-Kahlbaun in 1936 in an oil preparation for injectable use and introduced later that year as Progynon-B. Though it is still in widespread use today, it has been mostly superseded by newer forms of estradiol with improved pharmacokinetics that require less frequent administration such as estradiol cypionate and estradiol valerate.
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