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| Palmitoyl Pentapeptide |
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| Palmitoyl Pentapeptide |
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Palmitoyl Pentapeptide
(Skype:sales09_109)
Palmitoyl pentapeptide-4 (Matrixyl) is a skin rejuvenation compound developed by Sederma corporation in collaboration with Proctor & Gamble. It was originally named palmitoyl pentapeptide-3 and later renamed to palmitoyl pentapeptide-4 to reflect a correction in the data on its molecular structure. It has been included in a variety of commercial skin care formulas under the trademark Matrixyl. Please note that Matrixyl is distinct from its similar sounding distant cousin Matrixyl 3000.
The proponents claim that palmitoyl pentapeptide-4 is at least as effective against wrinkles as retinol but does not cause skin irritation, which is a common side-effect of retinoids.
So, is there any science under the hype? Chemically speaking, palmitoyl pentapeptide-4 (Pal-KTTKS) is a relatively small molecule. It consists of five amino acids linked together and attached to a fatty acid to enhance oil solubility for the sake of better skin penetration. It is structurally related to the precursor of collagen type I (a.k.a. procollagen type I). Researchers found that when added to the culture of fibroblasts (the key skin cells), palmitoyl pentapeptide-4 stimulated the synthesis of the key constituents of the skin matrix: collagen, elastin and glucosamnoglycans. How exactly palmitoyl pentapeptide-4 did that remains unclear, although a number of theories exist.
Unfortunately, the ability to improve the productivity of skin cells in the test tube, does not always translate into an effective anti aging treatment. Less than one in ten promising test tube discoveries ever becomes an established therapy. Clinical studies of palmitoyl pentapeptide-4 do exist but all of them (to my knowledge as of the day of this writing) have been conducted or sponsored by the manufacturers (Sedema and Proctor & Gamble). This does not necessarily make the studies biased, but potential conflict of interests is always a red flag. Unfortunately, this situation is typical. Early studies of patented chemicals are almost always sponsored by manufacturers. It usually takes a long time before completely independent research is conducted.
hot supply list:
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T-A015 Oxytocin 1g, 2mg//vial
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T-A018 176-191 2mg//vial
T-A019 Triptorelin 2mg//vial
T-A020 Tesamorelin 2mg//vial
T-A021 Gonadorelin 2mg//vial
T-A022 Gonadorelin 10mg//vial
T-A023 DSIP 2mg//vial
T-A024 Selank 5mg//vial
Email:sales09 at ycphar dom com
Skype:sales09_109
Telephone:86-027-50756084
Mobile:86-18872220656 |
 |
Palmitoyl Pentapeptide
(Skype:sales09_109)
Palmitoyl pentapeptide-4 (Matrixyl) is a skin rejuvenation compound developed by Sederma corporation in collaboration with Proctor & Gamble. It was originally named palmitoyl pentapeptide-3 and later renamed to palmitoyl pentapeptide-4 to reflect a correction in the data on its molecular structure. It has been included in a variety of commercial skin care formulas under the trademark Matrixyl. Please note that Matrixyl is distinct from its similar sounding distant cousin Matrixyl 3000.
The proponents claim that palmitoyl pentapeptide-4 is at least as effective against wrinkles as retinol but does not cause skin irritation, which is a common side-effect of retinoids.
So, is there any science under the hype? Chemically speaking, palmitoyl pentapeptide-4 (Pal-KTTKS) is a relatively small molecule. It consists of five amino acids linked together and attached to a fatty acid to enhance oil solubility for the sake of better skin penetration. It is structurally related to the precursor of collagen type I (a.k.a. procollagen type I). Researchers found that when added to the culture of fibroblasts (the key skin cells), palmitoyl pentapeptide-4 stimulated the synthesis of the key constituents of the skin matrix: collagen, elastin and glucosamnoglycans. How exactly palmitoyl pentapeptide-4 did that remains unclear, although a number of theories exist.
Unfortunately, the ability to improve the productivity of skin cells in the test tube, does not always translate into an effective anti aging treatment. Less than one in ten promising test tube discoveries ever becomes an established therapy. Clinical studies of palmitoyl pentapeptide-4 do exist but all of them (to my knowledge as of the day of this writing) have been conducted or sponsored by the manufacturers (Sedema and Proctor & Gamble). This does not necessarily make the studies biased, but potential conflict of interests is always a red flag. Unfortunately, this situation is typical. Early studies of patented chemicals are almost always sponsored by manufacturers. It usually takes a long time before completely independent research is conducted.
hot supply list:
Related product list
T-A001 MGF 2mg/vial
T-A002 PEG MGF 2mg/vial
T-A003 CJC-1295 with DAC 2mg/vial
T-A004 CJC-1295 without DAC 2mg/vial
T-A005 PT-141 10mg//vial
T-A006 MT-1 10mg//vial
T-A007 MT-2 10mg//vial
T-A008 GHRP-2 5mg//vial
T-A009 GHRP-2 10mg//vial
T-A010 GHRP-6 5mg//vial
T-A011 GHRP-6 10mg//vial
T-A012 Ipamorelin 2mg//vial
T-A013 Hexarelin 2mg//vial
T-A014 Sermorelin 2mg//vial
T-A015 Oxytocin 1g, 2mg//vial
T-A016 TB500 2mg//vial
T-A017 pentadecapeptide BPC 157 2mg//vial
T-A018 176-191 2mg//vial
T-A019 Triptorelin 2mg//vial
T-A020 Tesamorelin 2mg//vial
T-A021 Gonadorelin 2mg//vial
T-A022 Gonadorelin 10mg//vial
T-A023 DSIP 2mg//vial
T-A024 Selank 5mg//vial
Email:sales09 at ycphar dom com
Skype:sales09_109
Telephone:86-027-50756084
Mobile:86-18872220656 |
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