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JC Ampule
10-hydroxycamptothecin
64439-81-2
Pharmaceutical raw material.
Hydroxycamptothecin is a minor alkaloid isolated from Camptotheca acuminata (a tree native to mainland China). It and its close chemical relatives (amino camptothecin, CPT-11 , DX-8951f, and topotecan) are the only known natural-occurring DNA topoisomerase I inhibitors.
Molecular formula: C20H16N2O5
Molecular weight: 364.34
Appearance: yellow crystal
Insoluble in water, its sodium salt is the water soluble, its organic solution has blue fluorescence.
Melting point: 268-270oC
Assay: HPLC >98%
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