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| L-Theanine |
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| 5-N-Ethyl-L-glutamine, 99%, Powder |
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| 3081-61-6 |
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L-theanine is a non-protein amino acid mainly found naturally in the green tea plant (Camellia sinensis). L-theanine is the predominant amino acid in green tea and makes up 50% of the total free amino acids in the plant. The amino acid constitutes between 1% and 2% of the dry weight of green tea leaves. L-theanine is considered the main component responsible for the taste of green tea, which in Japanese is called umami. L-theanine is marketed in Japan as a nutritional supplement for mood modulation.
L-theanine is a derivative of L-glutamic acid. It is a water-soluble solid substance with the molecular formula C7H14O3 N and a molecular weight of 160.19 daltons. L-theanine is also known as gamma-ethylamino-L-glutamic acid, gamma-glutamylethylamide, r-glutamylethylamide, L-glutamic acid gamma-ethylamide and L-N-ethylglutamine.
L-theanine may have activity in modulating the metabolism of cancer chemotherapeutic agents and ameliorating their side effects. It may also have mood-modulating activity.
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L-theanine has exhibited anticancer effects and an ability to favorably modulate the activity of some anticancer drugs in in vitro and animal experiments. It has also demonstrated hypotensive effects in animal work. It has inhibited LDL-cholesterol oxidation in preliminary in vitro tests. It was recently reported to enhance learning ability in animals and to induce relaxation in human subjects, possibly through its effects on serotonin, dopamine and other neurotransmitters. It has also been shown to inhibit caffeine stimulation in another preliminary animal study.
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