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Dasatinib Monohydrate
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N -(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide monohydrate
[863127-77-9]
Dasatinib (BMS-354825) is a novel, oral, potent, multi-targeted kinase inhibitor of Bcr-Abl and Src family kinases (SFK) and is a promising cancer therapeutic agent. Preclinical data indicate that dasatinib is 325-fold more potent than imatinib against cells expressing wild-type Bcr-Abl, and that dasatinib is active against 18 of 19 Bcr-Abl mutations known to cause imatinib resistance
Description:Off-white to pale yellow power .

Solubility: Insoluble in water, slightly soluble in methanol and ethanol.

Related substances:Any single impurities: NMT0.5%
Total impurities: NMT1.0%

Assay(HPLC):min 99%

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Shanghai Yingxuan Pharmaceutical Science & Technology Co., LTD
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