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| Carboxymethyl Glucan |
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| CM-Glucan |
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APPLICATION:
CM-Glucan is the first cosmetic biochemical additive by improving skin's immunity system and a immune polysaccharide activator. It can activate immune cell, promote the synthesis of collagen, improve the elasticity of skin
recover the harm skin, anti-allergic, anti-inflammation and photo-protection, improve the effect of sunscreen product.
INTRODUCTION
Glucan is a poly beta (1-3)-linked glucopyranose of high molecular weight and belongs to the class of drugs known as biological response modifiers (BRMs). Glucan preparations are involved in the activation of the body's natural defence mechanisms and in wound healing processes of the skin. In the skin, Langerhans cells and keratinocytes are the immunologically active cells. Recent studies indicate that UV radiation can induce a depletion of the number and viability of these cells (immuno-suppression). The use of non-specific stimulators of immunocompetent cells, such as glucan, is a new approach to improve skin function under stress.
Cell culture experiments showed that CM-glucan protects skin cells against the depletion of antioxidant molecules upon UV-A irradiation and promotes the growth of keratinocytes. In placebo controlled studies with healthy volunteers, the pre-treatment of skin with CM-glucan offered substantial protection against skin damage caused by a detergent challenge of UV-A irradiation. In addition, CM-glucan enhanced the renewal rate of the stratum corneum.
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Chemical Name:Carboxymethyl Glucan
Molecular Weight:500,000-1,200,000
Structure Formula: C6H9O6-CH2COOH n
SPECIFICATION:
Appearance: Off-white powder
Odour : Light characteristic odour
pH (20 celsius degredd): 6.0~7.5
Ashes: not more than 22%
Substitute Degree: 60.0 ~80.0%
Loss on drying: not more than 10.0%
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