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�鳥怏特仲�?埰懿燼,9-[(R)-2-[[bis[[(isopropoxycarbonyl) oxy] methoxy] phosphinyl] methoxy] propyl] adenine fumarate">
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Tenofovir disoproxil fumarate
�鳥怏特仲�?埰懿燼
9-[(R)-2-[[bis[[(isopropoxycarbonyl) oxy] methoxy] phosphinyl] methoxy] propyl] adenine fumarate
202138-50-9
Tenofovir (Trade name Viread) is an anti-HIV drug approved by the FDA (In October of 2001) to be used in combination with other HIV fighting medications. Viread belongs to a new class of drugs called Nucleotide Reverse Transcriptase Inhibitors (NtRTI). These are related to Nucleoside Reverse Transcriptase Inhibitors (NRTI) like zidovudine (AZT, Retrovir). The body converts Viread into a chemical that prevent HIV from reproducing in uninfected cells, but it does not help cells that have already been infected with the virus. As people with HIV lose CD4 cells - one of the immune system's main defenses - they become more likely to get infections and illnesses.
Currently available anti-HIV drugs like AZT need three separate chemical steps before they are active. Viread needs only two chemical reactions (phosphorylation) to occur before it can start working. Partly due to this unique chemical feature, Viread also carries a "negative charge", allowing it to stay in the cells where it is active for a longer period. As a result, Viread only needs to be taken once a day.
Tenofovir disoproxil fumarate intermediates
Tenofovir
PMPA monohydrate 206184-49-8
DESMP 31618-90-3
(R)-9-(2-hydroxypropyl) adenine 14047-28-0 (R)-(+)-Propylene carbonate 16606-55-6
제품관련분야 의약,중간체
Changzhou Huaren Chemical Co.,Ltd.China
전화번호 86-13646148298
팩스번호 86-519-88104456
홈페이지 -
이메일 ph_chem@hotmail.com
주소 No.150,South Heping road, Changzhou city,Jiangsu, China,213003
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