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Cycloheximide(CAS#:66-81-9)
�鳥怏特仲�?埰懿燼
[1S-[1alpha(S),3alpha,5beta]]-4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2, 6- Piperidinedione
66-81-9
Cycloheximide (also known as actidione) is used as a selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. By binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi. But it is not active against prokaryotes. It is used in the selection of wild type genes. It is used as a plant growth regulator to stimulate ethylene production. It is used as a rodenticide and other animal pesticide. It is used as a media to detect to unwanted bacteria by suppressing yeasts and molds in beer fermentation. Some products such as nisin have this effective function as a preservative for food and beverage. But cycloheximide is highly toxic is not suitable for human use as a therapeutic antibiotic. Agricultural application also is decreasing due to the health risks. It is used as an agent effective against psoriasis.
SOLUBILITY IN WATER: 2-5 g/100ml (soluble in alcohol, chloroform, ether, acetone)
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